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Quinapril hydrochloride

CAT: 0013-GTR19161533-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161533-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Quinapril hydrochloride (Accupril) used in the treatment of hypertension and congestive heart failure. Quinapril is a prodrug. Quinapril is converted to its active metabolite, quinaprilat, in the liver. Quinapril inhibits angiotensin converting enzyme, an enzyme which catalyses the formation of angiotensin II from its precursor, angiotensin I. Angiotensin II is a powerful vasoconstrictor and increases blood pressure through a variety of mechanisms. Due to reduced angiotensin production, plasma concentrations of aldosterone are also reduced, resulting in increased excretion of sodium in the urine and increased concentrations of potassium in the blood. (In Vitro) :Quinapril (hydrochloride) (CI-906) is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure. Quinapril is rapidly de-esterified after absorption to quinaprilat (the active diacid metabolite), a potent angiotensin converting enzyme (ACE) inhibitor.
CAS Number
82586-55-8
Product Name Alternative
CI-906 | PD 109452-2
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 95 mg/mL (200.0 mM) ; Water: 95 mg/mL (200.0 mM) ; DMSO: 18 mg/mL (37.89 mM)
Smiles
CCOC (=O) [C@H] (CCC1=CC=CC=C1) N[C@@H] (C) C (=O) N2CC3=CC=CC=C3C[C@H]2C (=O) O.Cl
Molecular Formula
C25H31CIN2O5
Molecular Weight
474.98
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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