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Acumapimod

CAT: 0013-GTR19161510-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161510-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
An orally active, potent p38 MAPK inhibitor that potently inhibits ex vivo LPS‐induced TNFα secretion with an IC50 of 44 ng/mL (115 nM) ; inhibits LPS‐stimulated TNFα release in the human whole blood assay with IC50 of 24 nM; shows antiinflammatory activity for treatment of acute as opposed to chronic inflammation disorders.COPD Phase 1 Clinical.
CAS Number
836683-15-9
Product Name Alternative
BCT-197
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
O=C (NC1CC1) C2=CC=C (C) C (N3N=CC (C (C4=CC=CC (C#N) =C4) =O) =C3N) =C2
Molecular Formula
C22H19N5O2
Molecular Weight
385.4185
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, 3-[5-amino-4- (3-cyanobenzoyl) -1H-pyrazol-1-yl]-N-cyclopropyl-4-methyl-

Alternative Products

CatalogName
BA3652-5.1Acumapimod
A21325-100Acumapimod 100mg
A21325-25Acumapimod 25mg
A21325-1Acumapimod 1mg
A21325-50Acumapimod 50mg
A21325-10Acumapimod 10mg
A21325-5Acumapimod 5mg
319515Acumapimod (BCT-197)
A21325-10mM-DAcumapimod 10mM * 1mL in DMSO

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