Ciprofloxacin

CAT: 0013-GTR19161433-01Size: 500 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19161433-01Size:500 mg

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Description

Ciprofloxacin is a broad-spectrum antimicrobial carboxyfluoroquinoline. (In Vitro) :Ciprofloxacin (Bay-09867) (5-50 μg/mL; 0-24 h; tendon cells) inhibits cell proliferation and causes cell cycle arrest at the G2/M phase.Ciprofloxacin (Bay-09867) shows potent activity against Y. pestis and B. anthracis with MIC90 of 0.03 μg/mL and 0.12 μg/mL, respectively. (In Vivo) :Ciprofloxacin (Bay-09867) (30 mg/kg; i.p.; for 24 hours; BALB/c mice) has protection against Y. pestis in murine model of pneumonic plague.Ciprofloxacin (Bay-09867) (100 mg/kg; i.g.; daily, for 4 weeks; C57BL/6J mice) accelerates aortic root enlargement and increases the incidence of aortic dissection and rupture by decreases LOX level and increases MMP levels and activity in the aortic wall.Ciprofloxacin (Bay-09867) (100 mg/kg; i.g.; daily, for 4 weeks; C57BL/6J mice) induces DNA damage and release of DNA to the cytosol, mitochondrial dysfunction, and activation of cytosolic DNA sensor signaling. Ciprofloxacin lactate increases apoptosis and necroptosis in the aortic wall.

CAS Number

85721-33-1

Product Name Alternative

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Ethanol: <1 mg/mL (<1 mM) ; Water: <1 mg/mL (<1 mM) ; DMSO: <1 mg/mL (<1 mM)

Smiles

OC (C1=CN (c2c (C1=O) cc (F) c (N3CCNCC3) c2) C4CC4) =O

Molecular Formula

C17H18FN3O3

Molecular Weight

331.34

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1-cyclopropyl-6-fluoro-4-oxo-7- (piperazin-1-yl) -1,4-dihydroquinoline-3-carboxylic acid

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