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Oxantel Pamoate

CAT: 0013-GTR19160999-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160999-01Size:500 mg
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Description
Oxantel pamoate is used as Antinematodal Agent. (In Vivo) :The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI) =2.53) . Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively) . A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus.
CAS Number
68813-55-8
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
CN1CCCN=C1C=CC1=CC (O) =CC=C1.CN1CCCN=C1C=CC1=CC (O) =CC=C1.OC (=O) C1=C (CC2=C (C (O) =O) C (O) =CC3=CC=CC=C23) C2=CC=CC=C2C=C1O
Molecular Formula
C36H32N2O7
Molecular Weight
604.65
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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