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Fluconazole

CAT: 0013-GTR19160981-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19160981-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. (In Vitro) :Fluconazole inhibits 4 species ofAspergillus fumigatus with the IC50s of 23.9-43.5 μg/mL. Fluconazole (0.20 μg/mL) inhibits significantly the mycelial-phase growth and germ tube elongation of C. albicans in a medium supplemented with serum.Fluconazole is a triazole antifungal agent that has been available for the treatment of infections due to Candida, Cryptococcus. The MIC90 is highest for C. krusei (MIC ≥ 64 μg/mL) and C. glabrata (MIC, 32 μg/mL) and is ≤2 μg/mL for C. albicans (0.5 μg/mL), C. parapsilosis (2 μg/mL), C. tropicalis (2 μg/mL), C. lusitaniae (2 μg/mL), and C. kefyr (0.5 μg/mL) .Fluconazole (0.1-50.0 μg/mL) damages the fungal cells and reduces their viability. (In Vivo) :Fluconazole (0, 0.5, 1, 2.5, 5, 7.5, and 10 mg/kg; administered intraperitoneally (i.p.) as a single dose) results in a 50% reduction in fungal densities (ED50) of 4.87 mg/kg in a murine model of systemic candidiasis. Fluconazole exhibits terminal elimination half-life of 2.4 h) following i.p.
CAS Number
86386-73-4
Product Name Alternative
UK 49858
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 61 mg/mL (199.17 mM) ; DMSO: 61 mg/mL (199.17 mM)
Smiles
OC (CN1N=CN=C1) (C2=CC=C (F) C=C2F) CN3N=CN=C3
Molecular Formula
C13H12F2N6O
Molecular Weight
306.27
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (2,4-difluorophenyl) -1,3-bis (1,2,4-triazol-1-yl) propan-2-ol

Alternative Products

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C07715-01Fluconazole
E66B04103Rabbit ani-Fluconazole+Fluconazole

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