Products for Research Use Only
RegisterLogin

SRJ-23

CAT: 0013-GTR19160974-07Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19160974-07Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A novel semisynthetic derivative of andrographolide that directly target Ras to block the exchange of GDP for GTP and thus prevent Ras activation; significantly suppresses K-Ras GTP loading, whereas H-Ras and N-Ras GTP loading are much less sensitive; reduceds K-RasG12V GTP, phosphorylated ERK (ppERK) levels in K-RasG12V-transformed cells; induces G1 arrest and apoptosis in MCF-7 and HCT-116 cells, respectively.
CAS Number
865285-29-6
Product Name Alternative
SRJ23 | SRJ 23
Purity
>98% (HPLC)
Solubility
DMSO: Soluble (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (NC1=NN=NN1CCC) C2=CC=CC (Cl) =C2
Molecular Formula
C15H9ClFN3O2
Molecular Weight
317.704
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-Chloro-N-[5- (4-fluorophenyl) -1,3,4-oxadiazol-2-yl]-benzamide

Chemical Information

4-chloro-N-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)benzamide
CAS Number865285-29-6
PubChem CID4128171
IUPAC Name4-chloro-N-[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]benzamide
Molecular FormulaC15H9ClFN3O2
Molecular Weight317.70
XLogP3.3
Topological Polar Surface Area68
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count22
Formal Charge0
Complexity385
SMILES
C1=CC(=CC=C1C2=NN=C(O2)NC(=O)C3=CC=C(C=C3)Cl)F
InChI
InChI=1S/C15H9ClFN3O2/c16-11-5-1-9(2-6-11)13(21)18-15-20-19-14(22-15)10-3-7-12(17)8-4-10/h1-8H,(H,18,20,21)
InChIKey
ZIICPNCCHIUJSX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-chloro-N-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)benzamide
CAS: 865285-29-6
CID: 4128171
Formula: C15H9ClFN3O2
MW: 317.70
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight317.70
XLogP33.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass317.0367324
Monoisotopic Mass317.0367324
Topological Polar Surface Area68 Ų
Heavy Atom Count22
Formal Charge0
Complexity385
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR17965860Srj-38 Antibody
GTR19081448-01Recombinant Serpentine receptor class J-38 (srj-38)
GTR19022737-01Recombinant Mouse Interleukin-23/IL-23
GTR19154028-01TrkA inhibitor compound 23 (TrkA-IN-23)
GTR19218256-01ICMT-IN-23
GTR19217627-01FLT3-IN-23
GTR19211796-01DHODH-IN-23
GTR19209428-01HA-23
GTR19200713-01AZSMO-23
GTR19200544-01BMH-23

Alternative Products

CatalogName
MBS3606275-01SRJ-23
MBS1071050Recombinant Serpentine receptor class J-38 (srj-38)
MBS7179826Rabbit anti-Caenorhabditis elegans srj-38 Polyclonal Antibody
VAng-Ly3768-inquireRecombinant Caenorhabditis Elegans srj-38 Protein (aa 1-330)
I8443-42DInterleukin 23 (IL-23)
MBS343261-01Interleukin-23 (IL-23)
E21-S31Interleukin-23/IL-23
A0859-41BADAM 23 (A Disintegrin And Metalloproteinase 23)
446943-01Digoxigenin-21,23,23-d3
446934-01Digitoxigenin-21,23,23-d3

Popular Products