Products for Research Use Only
RegisterLogin

Amlodipine

CAT: 0013-GTR19160908-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19160908-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Amlodipine is a long-acting calcium channel blocker. Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells. (In Vitro) :Amlodipine (20-40 μM; 48 h) reduces BrdU incorporation to 68.6% and 26.3% at concentrations of 20 and 30 μM in A431 cells, respectively.Amlodipine (30 μM; pretreated for 1 h) significantly attenuates the uridine 5′-triphosphate (UTP) -induced increases of [Ca2+]i in A431 cells.Amlodipine (30 μM) inhibits the store-operated Ca2+influx evoked by Thapsigargin in Fluo-3-loaded cells. (In Vivo) :Amlodipine (5 mg/kg/day; s.c. for 2 weeks) significantly decreases systolic blood pressure (SBP) in VSMC ATP2B1 KO mice.Amlodipine (10 mg/kg; i.p. once daily for 20 days) causes a significant retardation of tumor growth and prolongs the survival of A431 tumor-bearing mice.
CAS Number
88150-42-9
Product Name Alternative
Intervask | Pelmec
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 82 mg/mL (200.54 mM) ; DMSO: 82 mg/mL (200.54 mM)
Smiles
OS (=O) (=O) C1=CC=CC=C1.CCOC (=O) C1=C (COCCN) NC (C) =C (C1C1=CC=CC=C1Cl) C (=O) OC
Molecular Formula
C20H25ClN2O5
Molecular Weight
408.88
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
B1410-50Amlodipine

Popular Products