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2'-Deoxyinosine

CAT: 0013-GTR19160888-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160888-01Size:200 mg
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Description
It is used to treat HIV infection with other antiviral drugs. (In Vitro) :In the absence of deoxycoformycin, 2’-deoxyadenosine is primarily deaminated to 2’-deoxyinosine and then converted into hypoxanthine. In the presence of the inhibitor, the deoxynucleoside, in addition to a phosphorylation process, undergoes phosphorolytic cleavage giving rise to adenine. The conversion of 2’-deoxyadenosine to adenine might represent a protective device, emerging when the activity of adenosine deaminase is reduced or inhibited. There is much evidence to indicate that the enzyme catalyzing this processs may be distinct from methylthioadenosine phosphorylase and S-adenosyl homocysteine hydrolase, which are the enzymes reported to be responsible for the formation of adenine from 28-deoxyadenosine in mammals.
CAS Number
890-38-0
Purity
>98% (HPLC)
Solubility
Limited solubility
Smiles
C1[C@@H] ([C@H] (O[C@H]1N2C=NC3=C2NC=NC3=O) CO) O
Molecular Formula
C10H12N4O4
Molecular Weight
252.23
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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