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GK921

CAT: 0013-GTR19160576-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160576-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GK921 is a transglutaminase 2 (TGase 2) inhibitor. GK921 showed cytotoxicity to RCC (average GI50 in eight RCC cell lines: 0.905 μM) . A single treatment with GK921 almost completely reduced tumor growth by stabilizing p53 in the ACHN and CAKI-1 preclinical xenograft tumor models. TGase 2 inhibitor GK921 abrogates RCC growth in xenograft tumor models, suggesting the possibility of a new therapeutic approach to RCC.
CAS Number
1025015-40-0
Product Name Alternative
GK921 | GK-921 | GK 921
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 30 mg/mL 87.11 mM
Smiles
C1CCN (C1) CCOc1c (nc2c (n1) cccn2) C#Cc1ccccc1
Molecular Formula
C21H20N4O
Molecular Weight
344.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3- (phenylethynyl) -2- (2- (pyrrolidin-1-yl) ethoxy) pyrido[2,3-b]pyrazine

Alternative Products

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BA7772-2GK921
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A21785-100GK921 100mg
A21785-50GK921 50mg
A21785-10GK921 10mg
A21785-25GK921 25mg
A21785-2GK921 2mg
A21785-10mM-DGK921 10mM * 1mL in DMSO

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