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TCS-PIM-1-4a

CAT: 0013-GTR19169034-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169034-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TCS-PIM-1-4a (SMI-4a) is a potent Pim kinase inhibitor that exhibits broad anti-leukemic activity. It induces cell death in diverse myeloid and lymphoid lines (IC50 0.8-40 μM) by activating AMPK to suppress mTORC1 signaling. This mechanism supports its use in vitro for studying hematological malignancies and related pathway interactions.
CAS Number
327033-36-3
Product Name Alternative
Cell-cycle, Bax, Bak, Apoptosis, arrest, 4E-BP1, mTORC1, inhibit, Inhibitor, Leukemic, SMI-4a, TCSPIM14a, TCS-PIM-1-4a, TCS PIM 1 4a, Pim kinases, Pim1, Pim2, Pim, p27Kip1
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
98.82% (May vary between batches)
Solubility
DMSO:55 mg/mL (201.3 mM)
Smiles
C (=C1SC (=O) NC1=O) C2=CC (C (F) (F) F) =CC=C2
Molecular Formula
C11H6F3NO2S
Molecular Weight
273.23
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
HY-16576TCS-PIM-1-4a
256890-01TCS PIM-1 4a
MBS386968-01TCS PIM-1 4a (SMI-4a)
A11967-25TCS PIM-1 4a 25mg
A11967-10TCS PIM-1 4a 10mg
A11967-50TCS PIM-1 4a 50mg
A11967-100TCS PIM-1 4a (SMI-4a) 100mg
A11967-5TCS PIM-1 4a (SMI-4a) 5mg
A11967-200TCS PIM-1 4a (SMI-4a) 200mg
A11967-10mM-DTCS PIM-1 4a 10mM * 1mL in DMSO

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