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COH000

CAT: 0013-GTR19168554-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168554-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
COH000 is an irreversible covalent inhibitor of the SUMO-activating enzyme, effectively blocking SUMOylation with an in vitro IC50 of approximately 0.2 μM. This compound is a valuable research tool for investigating SUMOylation's role in cellular processes such as stress response, cell cycle regulation, and DNA repair in both cellular and animal models.
CAS Number
1534358-79-6
Product Name Alternative
Ubiquitin-activating Enzyme E1, Ubiquitin ligase, Ubiquitin conjugating enzyme, Ubiquitin activating enzyme, Inhibitor, inhibit, E1 activating enzyme, E1/E2/E3 Enzyme, E1 Enzyme, E1Enzyme, E2 conjugating enzyme, E2 Enzyme, E3 ligating enzyme, E3Enzyme, E2Enzyme, E3 Enzyme, COH 000, COH000, COH-000
Field of Research
Protein Biochemistry
Purity
96.91% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:35.71 mg/mL (85.13 mM)
Smiles
[H][C@]12O[C@@] (C=C1) ([C@@H] (Cc1ccc (C) cc1) Nc1ccccc1) C (C (=O) OC) =C2C (=O) OC
Molecular Formula
C25H25NO5
Molecular Weight
419.47
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
BA7384-5COH000
A17122-100COH000 100mg
A17122-1COH000 1mg
A17122-2COH000 2mg
A17122-50COH000 50mg
A17122-5COH000 5mg
A17122-25COH000 25mg
A17122-10COH000 10mg
A17122-10mM-DCOH000 10mM * 1mL in DMSO

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