Products for Research Use Only

RHPS4

CAT: 0013-GTR19167911-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167911-01Size:5 mg
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Description
RHPS4 methosulfate is a submicromolar-potency telomerase inhibitor. It is a research tool used in vitro and in vivo to study telomere biology, cellular senescence, and oncology, particularly in the context of cancer therapeutics.
CAS Number
390362-78-4
Product Name Alternative
RHPS 4, RHPS4, RHPS-4, Telomerase, CG5, Apoptosis, NSC714187, NSC-714187, NSC 714187, M14, PC3, HT29, H2AX, H460
Field of Research
Cell Biology, Molecular Biology
Purity
98.59% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:4.9 mg/mL (10.69 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
COS ([O-]) (=O) =O.Cc1cc2n (C) c3ccc (F) cc3c3[n+] (C) c4ccc (F) cc4c (c1) c23
Molecular Formula
C22H17F2N2·CH3O4S
Molecular Weight
458.48
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

RHPS 4 methosulfate
CAS Number390362-78-4
PubChem CID9804187
IUPAC Name4,16-difluoro-8,11,20-trimethyl-8-aza-20-azoniapentacyclo[11.7.1.02,7.09,21.014,19]henicosa-1(20),2(7),3,5,9,11,13(21),14(19),15,17-decaene;methyl sulfate
Molecular FormulaC23H20F2N2O4S
Molecular Weight458.5
Topological Polar Surface Area81.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count0
Heavy Atom Count32
Formal Charge0
Complexity633
SMILES
CC1=CC2=C3C(=C1)N(C4=C(C3=[N+](C5=C2C=C(C=C5)F)C)C=C(C=C4)F)C.COS(=O)(=O)[O-]
InChI
InChI=1S/C22H17F2N2.CH4O4S/c1-12-8-16-15-10-13(23)4-6-18(15)26(3)22-17-11-14(24)5-7-19(17)25(2)20(9-12)21(16)22;1-5-6(2,3)4/h4-11H,1-3H3;1H3,(H,2,3,4)/q+1;/p-1
InChIKey
VRWGYMXWYZBBGF-UHFFFAOYSA-M
Chemical Structure
2D Structure
2D structure of RHPS 4 methosulfate
CAS: 390362-78-4
CID: 9804187
Formula: C23H20F2N2O4S
MW: 458.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight458.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count0
Exact Mass458.11118462
Monoisotopic Mass458.11118462
Topological Polar Surface Area81.9 Ų
Heavy Atom Count32
Formal Charge0
Complexity633
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes