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GSK778 hydrochloride

CAT: 0013-GTR19166825-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166825-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK778 hydrochloride is a potent and selective BD1 bromodomain inhibitor of BET proteins, demonstrating low nanomolar IC50 values. It mimics pan-BET inhibitor effects in cancer models, making it a valuable tool for epigenetic research in oncology, applicable in both cellular and in vivo studies of transcriptional regulation and tumor progression.
CAS Number
2863657-79-6
Product Name Alternative
BET, EpigeneticReaderDomain, Epigenetic Reader Domain, GSK-778 Hydrochloride, GSK778 Hydrochloride, GSK778 hydrochloride, GSK 778 Hydrochloride
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
97.26% (May vary between batches)
Solubility
DMSO:50 mg/mL (91.23 mM)
Smiles
C[C@@H] (N1C (COC) =NC2=C1C3=CC (OC[C@@H]4CNCC4) =C (C5=C (C) ON=C5C) C=C3N=C2) C6=CC=CC=C6.[H]Cl
Molecular Formula
C30H34ClN5O3
Molecular Weight
548.08
Storage Conditions
-20°C
Notes
For research use only.

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