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SHR0302

CAT: 0013-GTR19165726-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19165726-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHR0302 (ARQ252) is a selective JAK1 inhibitor, demonstrating >10-fold selectivity over JAK2, 77-fold over JAK3, and 420-fold over Tyk2. This small molecule is a valuable research tool for investigating JAK1-dependent pathways in both cellular and animal models of autoimmune and inflammatory diseases.
CAS Number
1445987-21-2
Product Name Alternative
Collagen, B-cell, arthritis, ARQ252, ARQ-252, ARQ 252, anti-inflammatory, anti-proliferation, Apoptosis, Inhibitor, Janus kinase, JAK1, JAK1-STAT3, JAK, inhibit, migration, fibrosis, hepatic, SHR 0302, SHR0302, SHR-0302, phosphorylation, Th17
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.11% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.83 mM) ; DMSO:30 mg/mL (72.38 mM)
Smiles
[H][C@@]12C[C@H] (C[C@]1 ([H]) CN (C2) C (=O) Nc1nc (OC) ns1) N (C) c1ncnc2[nH]ccc12
Molecular Formula
C18H22N8O2S
Molecular Weight
414.48
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
BUP03096-01SHR0302

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