Products for Research Use Only

Thymidine

CAT: 0013-GTR19164442-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164442-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thymidine (DThyd) is a nucleoside used to synchronize cell populations by reversibly inhibiting DNA synthesis, inducing G1/S phase arrest. It serves as a specific DNA precursor in research applications, including studies of cell cycle dynamics, DNA replication, and cytotoxicity in both in vitro and in vivo models.
CAS Number
50-89-5
Product Name Alternative
Endogenous Metabolite, EndogenousMetabolite, Inhibitor, inhibit, NSC 21548, NSC21548, NSC-21548, arrest, 5-Methyldeoxyuridine, Deoxyribothymidine, DNA, DThyd, DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, synchronizing, replication, RNA Synthesis, RNASynthesis, Thymidin, Thymidine, precursor
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology
Purity
≥95% (May vary between batches)
Solubility
Pyridine, Methanol, etc.:Soluble; DMSO:245 mg/mL (1011.44 mM) ;5% DMSO+95% Saline:2.63 mg/mL (10.86 mM) ;10% DMSO+90% Saline:5 mg/mL (20.64 mM) ; Saline:25 mg/mL (103.21 mM) ; Ethanol:< 1 mg/mL (insoluble)
Smiles
O=C1N ([C@@H]2O[C@H] (CO) [C@@H] (O) C2) C=C (C) C (=O) N1
Molecular Formula
C10H14N2O5
Molecular Weight
242.23
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

Chemical Information

Thymidine

Thymidine is a pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase. It has a role as a metabolite, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is functionally related to a thymine. It is an enantiomer of a telbivudine.

CAS Number50-89-5
PubChem CID5789
IUPAC Name1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Molecular FormulaC10H14N2O5
Molecular Weight242.23
XLogP-1.2
Topological Polar Surface Area99.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count17
Formal Charge0
Complexity381
SMILES
CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O
InChI
InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChIKey
IQFYYKKMVGJFEH-XLPZGREQSA-N
Chemical Structure
2D Structure
2D structure of Thymidine
CAS: 50-89-5
CID: 5789
Formula: C10H14N2O5
MW: 242.23
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight242.23
XLogP3-1.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass242.09027155
Monoisotopic Mass242.09027155
Topological Polar Surface Area99.1 Ų
Heavy Atom Count17
Formal Charge0
Complexity381
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes