Products for Research Use Only
RegisterLogin

N-Ethylmaleimide

CAT: 0013-GTR19163925-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19163925-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies. (In Vitro) :N-Ethylmaleimide (20 μM;30 min) inhibits Akt Ser-473, Akt Thr-308 , p70S6K, ribosomal protein S6, 4E-BP1, eIF4E, BAD and FKHR-L1 phosphorylation.N-Ethylmaleimide (20 μM;30 min) affects conversion of pro-caspase-3 in vascular smooth muscle cells.N-Ethylmaleimide (20 μM;6 h) promotes vascular smooth muscle cells apoptosis.N-Ethylmaleimide (20 μM;30 min) affects PP2A activity and ROS production in vascular smooth muscle cells. (In Vivo) :N-Ethylmaleimide (10 mg/kg; i.h.) promotes the prevalence situation of mice with acute gastric ulcers.
CAS Number
128-53-0
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
CCN1C (=O) C=CC1=O
Molecular Formula
C6H7NO2
Molecular Weight
125.13
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

N-Ethylmaleimide

N-ethylmaleimide is a member of the class of maleimides that is the N-ethyl derivative of maleimide. It has a role as an anticoronaviral agent, an EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor, an EC 2.7.1.1 (hexokinase) inhibitor and an EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor. It is functionally related to a maleimide.

CAS Number128-53-0
PubChem CID4362
IUPAC Name1-ethylpyrrole-2,5-dione
Molecular FormulaC6H7NO2
Molecular Weight125.13
XLogP0.9
Topological Polar Surface Area37.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count9
Formal Charge0
Complexity165
SMILES
CCN1C(=O)C=CC1=O
InChI
InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
InChIKey
HDFGOPSGAURCEO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-Ethylmaleimide
CAS: 128-53-0
CID: 4362
Formula: C6H7NO2
MW: 125.13
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight125.13
XLogP30.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass125.047678466
Monoisotopic Mass125.047678466
Topological Polar Surface Area37.4 Ų
Heavy Atom Count9
Formal Charge0
Complexity165
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19246649-01N, N, N′, N′-Tetramethylethylenediamine
GTR19244870-01N, N, N', N'-Tetramethylchloroformamidinium hexafluorophosphate
GTR19257502-01N, N', N''-Triacetylchitotriose
GTR19244933-01N, N, N-Trimethylethanaminium iodide
GTR19247943-01N, N-Dimethyldecylamine N-oxide
GTR19244737N, N, N-Trimethylbenzenaminium chloride
GTR19188378-01Nε, Nε, Nε-Trimethyllysine chloride
GTR19250963-01N'-benzyl-N, N-dimethylethylenediamine
GTR19225172-01N, N'-DME-N, N'-Bis-PEG2-acid
GTR19246624-014-Methylumbelliferyl β-D-N, N', N'', N'''-tetraacetylchitotetraoside

Alternative Products

CatalogName
GK7362-5gN-Ethylmaleimide
705003N‐ETHYLMALEIMIDE
EB0450N-Ethylmaleimide (NEM)
E12020-01N-Ethylmaleimide 98%
HY-D0843R-01N-Ethylmaleimide (Standard)
C09528-25mgNEM (N-Ethylmaleimide)

Popular Products