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EPZ-015866

CAT: 0013-GTR19162973-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19162973-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EPZ-015866 (GSK-591, GSK-3203591) is a potent, selective protein methyltransferase 5 (PRMT5) inhibitor with IC50 of 4 nM; shows excellent selectivity against other PMT enzymes observed with EPZ015666; inhibits the proliferation of Z-138 cells with IC50 of 62 nM.
CAS Number
1616391-87-7
Product Name Alternative
GSK-591 | GSK-3203591
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (NC[C@H] (O) CN1CCC (C=CC=C2) =C2C1) C3=CC (NC4CCC4) =NC=C3
Molecular Formula
C22H28N4O2
Molecular Weight
380.4833
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-Pyridinecarboxamide, 2- (cyclobutylamino) -N-[ (2S) -3- (3,4-dihydro-2 (1H) -isoquinolinyl) -2-hydroxypropyl]-

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