Products for Research Use Only
RegisterLogin

IQ-1S

CAT: 0013-GTR19162624-01Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19162624-01Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent, highly specific JNK inhibitor with IC50 of 390, 360, and 87 nM for JNK1, JNK2, and JNK3, respectively; does not inhibits other kinases that represent potential targets for RA treatment, including GSK-3beta, JAK2, JAK3, PI3Ks, Btk, IKK-2, etc.; inhibits pro-inflammatory cytokine (IL-1α, IL-1β, IL-6, IL-10, TNF-α, IFN-γ, and GM-CSF and nitric oxide production by human and murine monocyte/macrophages; inhibits LPS-induced TNF-α and IL-6 production in MonoMac-6 cells with IC50 of 0.25 and 0.61 uM, respectively; reduces inflammation and cartilage loss associated with CIA in mice model.
CAS Number
23146-22-7
Product Name Alternative
IQ 1S free acid
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 32 mg/mL
Smiles
O/N=C1C2=C (C3=NC4=CC=CC=C4N=C3\1) C=CC=C2
Molecular Formula
C15H9N3O
Molecular Weight
247.2515
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
11H-Indeno[1,2-b]quinoxalin-11-one, oxime

Related Products

CatalogName
GTR19234986Me-IQ
GTR19166102-01IQ-3
GTR19162566-01IQ-1
GTR19319228-01IQ-R
GTR19171063-01IQ 1
GTR19153827-01IQ-1
GTR19255685-01N-Acetoxy-IQ
GTR19192080(1S) -Calcitriol
GTR19257772-011S-LSD
GTR19182727(1S) -Chrysanthemolactone

Alternative Products

CatalogName
452455-01IQ 1S
B1279-5IQ-1S
A16062-100IQ-1S 100mg
A16062-25IQ-1S 25mg
A16062-200IQ-1S 200mg
A16062-500IQ-1S 500mg
A16062-50IQ-1S 50mg
A16062-10IQ-1S 10mg
A16062-5IQ-1S 5mg

Popular Products