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Cefsulodine sodium

CAT: 0013-GTR19162171-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162171-01Size:500 mg
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Description
Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics. (In Vitro) :Cefsulodin sodium (0.5-64 mg/mL; 18 h) is active in minimum inhibitory concentrations (MICs) of 0.5-64 mg/mL, is about 16- to 32-fold more active than Carbenicillin (HY-B0525) against Psuedomonas aeruginosa.Cefsulodin sodium (8-16 μg/mL; 4.5 h) is not hydrolyzed by the beta-lactamase induced in P. aeruginosa by growth in the presence of benzylpenicillin. (In Vivo) :Cefsulodin sodium (1 g/kg/tag; i.p.; 5 d, 9 single doses with intervals of 12 h) shows a increasing excretion of tubule cells in the rat, as a measure of nephrotoxicity, and displays tubule toxic threshold doses of 250 mg/kg (s.c.; 12 d) with nine single doses.
CAS Number
52152-93-9
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
O=C (C (N12) =C (C[N+]3=CC=C (C (N) =O) C=C3) CS[C@]2 ([H]) [C@H] (NC ([C@@H] (C4=CC=CC=C4) S (=O) ([O-]) =O) =O) C1=O) [O-].[Na+]
Molecular Formula
C22H19N4NaO8S2
Molecular Weight
554.52
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Sodium (6R,7R) -3- ((4-carbamoylpyridin-1-ium-1-yl) methyl) -8-oxo-7- ((R) -2-phenyl-2-sulfonatoacetamido) -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

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