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PRIMA-1

CAT: 0013-GTR19161998-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19161998-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A specific mutant p53 reactivator that induces apoptosis and enhances chemotherapeutic cytotoxicity in cancer cell lines; is efficacious against myeloma cells with differential p53 genotypes, causes the demethylation of TP73, through DNMT1 depletion, to subsequently enhance UPR; selectively induces apoptosis and cell cycle arrest in p53 mutant cells compared to CAPAN-2 cells.Blood Cancer Phase 2 Clinical.
CAS Number
5608-24-2
Product Name Alternative
PRIMA 1 | PRIMA1
Field of Research
Neuroscience
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 44 mg/mL
Smiles
O=C1C (CO) (CO) N2CCC1CC2
Molecular Formula
C9H15NO3
Molecular Weight
185.2203
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-Azabicyclo[2.2.2]octan-3-one, 2,2-bis (hydroxymethyl) -

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