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Atopaxar hydrobromide

CAT: 0013-GTR19161937-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161937-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, reversible PAR-1 antagonist with IC50 of 19 nM; shows potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC50 of 64 nM and 31 nM, respectively, with no effect on platelet aggregation induced by either ADP or collagen; inhibits arterial thrombosis without affecting bleeding time in photochemically-induced thrombosis model guinea pigs.Thrombosis Phase 2 Clinical.
CAS Number
474550-69-1
Product Name Alternative
E5555 hydrobromide
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
COC1=C (N2CCOCC2) C=C (C (CN (CC3=C4C (F) =C (OCC) C (OCC) =C3) C4=N) =O) C=C1C (C) (C) C.[H]Br
Molecular Formula
C29H38FN3O5.HBr
Molecular Weight
608.54
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (5,6-Diethoxy-7-fluoro-1,3-dihydro-1-imino-2H-isoindol-2-yl) -1-[3- (1,1-dimethylethyl) -4-methoxy-5- (4-morpholinyl) phenyl]ethanone hydrobromide

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