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Sulfamethoxazole

CAT: 0013-GTR19161653-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19161653-01Size:1 g
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Description
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. Target: Antibacterial Sulfonamides are structural analogs and competitive antagonists of para-aminobenzoic acid (PABA) . (In Vitro) :Sulfonamides are structural analogs and competitive antagonists of para-aminobenzoic acid (PABA) . They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Bacterial resistance to sulfamethoxazole is caused by mutations in the enzymes involved in folic acid synthesis that prevent the drug from binding to it.
CAS Number
723-46-6
Product Name Alternative
NSC 147832 | Ro 4-2130
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 23 mg/mL (90.8 mM) ; DMSO: 51 mg/mL (201.35 mM)
Smiles
CC1=CC (NS (=O) (C2=CC=C (N) C=C2) =O) =NO1
Molecular Formula
C10H11N3O3S
Molecular Weight
253.28
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-amino-N- (5-methylisoxazol-3-yl) benzenesulfonamide

Alternative Products

CatalogName
B2040-50Sulfamethoxazole
T200416-01Sulfamethoxazole-NO

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