Products for Research Use Only

Dermofongin

CAT: 0013-GTR19163899-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19163899-01Size:1 g
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Description
5-Chloro-8-hydroxyquinoline, also called Cloxiquine, has the efficancy of anti-viral. (In Vitro) :Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis.Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells. (In Vivo) :Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
CAS Number
130-16-5
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
OC1=C2N=CC=CC2=C (Cl) C=C1
Molecular Formula
C9H6ClNO
Molecular Weight
179.6
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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