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Ledipasvir

CAT: 0013-GTR19160846-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19160846-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ledipasvir, also known as GS-5885; is an inhibitor of the hepatitis C virus NS5A protein and is a drug for the treatment of hepatitis C that was developed by Gilead Sciences. On October 10, 2014 the FDA approved the combination product ledipasvir 90 mg/sofosbuvir 400 mg (trade name Harvoni) . The ledipasvir/sofosbuvir combination is a direct-acting antiviral agent that interferes with HCV replication and can be used to treat patients with genotypes 1a or 1b without PEG-interferon or ribavirin.
CAS Number
1256388-51-8
Product Name Alternative
GS5885 | GS-5885 | GS 5885 | Ledipasvir
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : 50 mg/mL. 56.24 mM; H2O : < 0.1 mg/mL
Smiles
O=C (OC) N[C@H] (C (=O) N1[C@H] (c2ncc (c3cc4C (F) (F) c5c (ccc (c6ccc7nc ([C@H]8N (C (=O) [C@@H] (NC (=O) OC) C (C) C) [C@@H]9CC[C@H]8C9) [nH]c7c6) c5) c4cc3) [nH]2) CC2 (C1) CC2) C (C) C
Molecular Formula
C49H54F2N8O6
Molecular Weight
889
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Methyl N-[ (2S) -1-[ (6S) -6-[5-[9,9-Difluoro-7-[2-[ (1S,2S,4R) -3-[ (2S) -2- (methoxycarbonylamino) -3-methylbutanoyl]-3-azabicyclo[2.2.1]heptan-2-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate

Alternative Products

CatalogName
A3546-5Ledipasvir
HY-15602DLedipasvir (diacetone)
TRC-L320105-50MGLedipasvir Impurity A
PC110123Ledipasvir Intermediate
TRC-L320102-25MGLedipasvir-d6
C10139Ledipasvir acetone
C12792-5mgLedipasvir (GS5885)
CS-O-13775Ledipasvir D16
CKC65548-01Ledipasvir diacetone
T4203-01Ledipasvir (acetone)

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