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PF-4989216

CAT: 0013-GTR19160746-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160746-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-4989216 is a novel potent and selective PI3K inhibitor. PF-4989216 inhibits the phosphorylation of PI3K downstream molecules and subsequently leads to inhibition in cell proliferation and xenograft tumor growth in NSCLCs harboring a PIK3CA mutation, including an erlotinib resistant line, NCI-H1975. PF-4989216 inhibited PI3K downstream signaling and subsequently led to apoptosis induction, and inhibition in cell viability, transformation, and xenograft tumor growth in SCLCs harboring PIK3CA mutation.
CAS Number
1276553-09-3
Product Name Alternative
PF4989216 | PF 4989216 | PF-4989216
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 29 mg/mL. 76.24 mM
Smiles
FC1=C (C=CC (=C1) C#N) C1=C (SC (N2CCOCC2) =C1C#N) C1=NC=NN1
Molecular Formula
C18H13FN6OS
Molecular Weight
380.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (4-cyano-2-fluorophenyl) -2-morpholino-5- (1H-1,2,4-triazol-5-yl) thiophene-3-carbonitrile

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Alternative Products

CatalogName
B5948-10PF-4989216
A12889-100PF-4989216 100mg
A12889-50PF-4989216 50mg
A12889-5PF-4989216 5mg
A12889-25PF-4989216 25mg
A12889-2PF-4989216 2mg

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