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NVP-TNKS656

CAT: 0013-GTR19160532-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160532-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NVP-TNKS656, also known as TNKS656, is a potent and orally active Tankyrase Inhibitor. With an enthalpy-driven thermodynamic signature of binding, highly favorable physicochemical properties, and high lipophilic efficiency, NVP-TNKS656 is well suited for further in vivo validation studies. Bioactivity of TNKS656: TNKS2 IC50 = 6nM, LiPE = 7.0, HEK298 STF IC50 = 3.5nM, Cmax/ Cellular IC50 = 23,000.
CAS Number
1419949-20-4
Product Name Alternative
NVPTNKS656 | TNKS656 | TNKS656
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 40 mg/mL. 80.88 mM
Smiles
COc1ccc (cc1) C (=O) C1CCN (CC (=O) N (CC2CC2) Cc2nc (=O) c3c (CCOC3) [nH]2) CC1
Molecular Formula
C27H34N4O5
Molecular Weight
494.58
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (cyclopropylmethyl) -2- (4- (4-methoxybenzoyl) piperidin-1-yl) -N- ((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl) methyl) acetamide

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Alternative Products

CatalogName
B6046-10NVP-TNKS656

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