Products for Research Use Only

FRAX1036

CAT: 0013-GTR19160522-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160522-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FRAX1036 is a potent and selective PAK1 inhibitor. Administration of docetaxel with either FRAX1036, or PAK1 small interfering RNA oligonucleotides dramatically altered signaling to cytoskeletal-associated proteins, such as stathmin, and induced microtubule disorganization and cellular apoptosis. Live-cell imaging revealed that the duration of mitotic arrest mediated by docetaxel was significantly reduced in the presence of FRAX1036, and this was associated with increased kinetics of apoptosis.
CAS Number
1432908-05-8
Product Name Alternative
FRAX1036 | FRAX-1036 | FRAX 1036
Purity
>98% (HPLC)
Solubility
DMSO : 5.3 mg/mL. 10.23 mM
Smiles
CCn1c2nc (ncc2cc (c1=O) c1c (cc (cc1) c1cncc (n1) C) Cl) NCCC1CCN (CC1) C
Molecular Formula
C28H32ClN7O
Molecular Weight
518.05
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6- (2-chloro-4- (6-methylpyrazin-2-yl) phenyl) -8-ethyl-2- ((2- (1-methylpiperidin-4-yl) ethyl) amino) pyrido[2,3-d]pyrimidin-7 (8H) -one

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