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Goserelin acetate

CAT: 0013-GTR19160510-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160510-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Goserelin acetate is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer. (In Vitro) :Goserelin (1 nM-1 mM; 48-72 hours) promotes EOC cell apoptosis.Goserelin (100 μM; 24-72 hours) regulates the expression of human apoptosis-related genes in SKOV3-ip cells.Goserelin (100 μM; 24-72 hours) promotes EOC cell apoptosis by upregulating FOXO1 through the PI3K/AKT signaling pathway. (In Vivo) :Goserelin (100 μg; s.c.; daily; for 19 days) significantly increases the proportion of apoptotic cells in the subcutaneous xenograft tumors.
CAS Number
145781-92-6
Product Name Alternative
ICI-118630 acetate
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 28 mg/mL; 21.06 mM
Smiles
CC (C) C[C@@H] (C (=O) N[C@@H] (CCCN=C (N) N) C (=O) N1CCC[C@H]1C (=O) NNC (=O) N) NC (=O) [C@@H] (COC (C) (C) C) NC (=O) [C@H] (Cc1ccc (cc1) O) NC (=O) [C@H] (CO) NC (=O) [C@H] (Cc1c[nH]c2ccccc12) NC (=O) [C@H] (Cc1cnc[nH]1) NC (=O) [C@@H]1CCC (=O) N1.CC (=O) O
Molecular Formula
C61H88N18O16
Molecular Weight
1329.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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Alternative Products

CatalogName
IZB49497-01Goserelin acetate
HY-13673A-01Goserelin (acetate)
A15959-100Goserelin Acetate 100mg
A15959-5Goserelin Acetate 5mg
A15959-25Goserelin Acetate 25mg
sc-491506Goserelin Deuterated Acetate
A15959-50Goserelin Acetate 50mg
A15959-10Goserelin Acetate 10mg
A15959-2Goserelin Acetate 2mg
A15959-10mM-DGoserelin Acetate 10mM * 1mL in DMSO

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