Products for Research Use Only

CVT-313

CAT: 0013-GTR19160409-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160409-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CVT-313 is a potent and selective inhibitor of CDK2 that prevents neointimal proliferation. CVT-313 has an IC50 of 0.5 microM in vitro. Inhibition was competitive with respect to ATP (Ki = 95 nM), and selective CVT-313 had no effect on other, nonrelated ATP-dependent serine/threonine kinases. The growth of mouse, rat, and human cells in culture was also inhibited by CVT-313 with the IC50 for growth arrest ranging from 1.25 to 20 microM. CVT-313 is a promising candidate for evaluation in other disease models related to aberrant cell proliferation.
CAS Number
199986-75-9
Product Name Alternative
CVT-313 | CVT 313 | CVT313
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL; 249.71 mM
Smiles
CC (C) n1cnc2c1nc (nc2NCc1ccc (cc1) OC) N (CCO) CCO
Molecular Formula
C20H28N6O3
Molecular Weight
400.47
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2,2'- ((9-isopropyl-6- ((4-methoxybenzyl) amino) -9H-purin-2-yl) azanediyl) bis (ethan-1-ol)

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