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RO1138452

CAT: 0013-GTR19160389-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160389-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RO1138452 is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3) . It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Likewise, it inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki of about 1.5 nM. At levels between 2-20 mg/kg in rats, CAY10441 shows significant analgesic activity in standard antinociceptive assays.
CAS Number
221529-58-4
Product Name Alternative
CAY10441
Purity
>98% (HPLC)
Solubility
DMSO : 33.33 mg/mL. 107.72 mM; H2O : < 0.1 mg/mL
Smiles
CC (C) Oc1ccc (Cc2ccc (NC3=NCCN3) cc2) cc1
Molecular Formula
C19H23N3O
Molecular Weight
309.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
BA5698-50RO1138452
HY-108912R-01RO1138452 (Standard)

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