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Alfacalcidol

CAT: 0013-GTR19160331-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160331-01Size:200 mg
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Description
Alfacalcidol is an active metabolite of Vitamin D, which performs important functions in regulation of the calcium balance and the bone metabolism. Alfacalcidol is Vitamin D-hormone analog which is activated by the enzyme 25-hydroxylase in the liver for systemic and in osteoblasts for local D-hormone actions. It possesses a unique pattern of pleiotropic effects on, e.g. gut, bone, pararthyroids, muscle and brain. Alfacalcidol is superior to plain vitamin D (cholecalciferol) because the final kidney activation of the latter is regulated by a negative feedback mechanism.
CAS Number
41294-56-8
Product Name Alternative
1-hydroxycholecalciferol | 1.alpha.-Hydroxyvitamin D3
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 50 mg/mL. 124.80 mM; H2O : < 0.1 mg/mL
Smiles
[H][C@@]12CC[C@H] ([C@H] (C) CCCC (C) C) [C@@]1 (C) CCC\C2=C\C=C1/C[C@@H] (O) C[C@H] (O) C1=C
Molecular Formula
C27H44O2
Molecular Weight
400.64
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(1R,3S,5Z) -5-[ (2E) -2-[ (1R,3aS,7aR) -7a-methyl-1-[ (2R) -6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

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