Ticlopidine

CAT: 0013-GTR19160300-01Size: 1 gDry Ice: NoHazardous: No

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CAT#:0013-GTR19160300-01Size:1 g

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Description

Ticlopidine is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor. (In Vitro) :Ticlopidine exhibits activity against human CD39 with apparent Ki, app values of 14 μM.Ticlopidine inhibits recombinant human CD39 expressed in COS-7-cells with the Ki value of 127±12 μM.Growth rate is affected during the first days of culture, Ticlopidine (30 and 150 μM) reducing its effect in the following days. (In Vivo) :Oral administration of Losartan with 10 mg/kg Ticlopidine significantly increases the AUC (by 65.0%), suggesting that Ticlopidine can effectively inhibit the metabolism of losartan in the intestine and/or liver.

CAS Number

55142-85-3

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : ≥ 100 mg/mL (379.09 mM)

Smiles

C1CN (Cc2c1scc2) Cc1ccccc1Cl

Molecular Formula

C14H14ClNS

Molecular Weight

263.78

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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Ticlopidine

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