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ICA069673

CAT: 0013-GTR19160292-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19160292-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ICA069673 is a heteromeric Kv7 channel activator. It is selective for Kv7.2/7.3 over Kv7.3/7.5 (EC50s = 0.69 and 14.3 μM, respectively) . ICA-069673 inhibited spontaneous phasic, pharmacologically induced, and nerve-evoked contractions in DSM isolated strips in a concentration-dependent manner. ICA-069673 decreased the global intracellular Ca (2+) concentration in DSM cells, an effect blocked by the L-type Ca (2+) channel inhibitor nifedipine. ICA-069673 hyperpolarized the membrane potential and inhibited spontaneous action potentials of isolated DSM cells, effects that were blocked in the presence of XE991.
CAS Number
582323-16-8
Product Name Alternative
ICA-069673 | ICA 069673 | ICA069673
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 34 mg/mL; 126.10 mM
Smiles
C1cc (c (cc1C (=O) Nc1cnc (nc1) Cl) F) F
Molecular Formula
C11H6CLF2NO3
Molecular Weight
269.63
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (2-chloro-5-pyrimidinyl) -3,4-difluoro-benzamide

Alternative Products

CatalogName
530943ICA069673

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