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Veratric acid

CAT: 0013-GTR19160143-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160143-01Size:200 mg
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Description
Veratric acid plays an important role in producing antibiotics and various dyes. They are used as intermediates for pharmaceuticals (especially for antipyretic analgesic, anti-rheumatism) and other organic syntheses. It is used as a matrix for ionization of peptides, proteins, and carbohydrates. (In Vitro) :Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation and HDAC3 expression in RAW264.7 cells.Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis.Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation. (In Vivo) :Veratric acid (40 mg/kg, p.o., b.w.) significantly promotes ventricular function, reduces lipid peroxidation and increases antioxidants in l-NAME-induced hypertensive rats.
CAS Number
93-07-2
Product Name Alternative
3,4-Dimethoxybenzoic acid
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (548.94 mM)
Smiles
COc1c (cc (cc1) C (=O) O) OC
Molecular Formula
C9H10O4
Molecular Weight
182.17
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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