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Fluorometholone Acetate

CAT: 0013-GTR19160138-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160138-01Size:200 mg
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Description
Fluorometholone acetate is an anti-inflammatory that may be useful in the reduction of ocular inflammation. (In Vitro) :For Fluorometholone acetate, a Ki value from Lineweaver-Burk plots is obtained as 1.044 μM (noncompetitive) for hCA-I and 9.98 μM (non-competitive) for hCA-II. (In Vivo) :Hourly topical administration of 0.1% Fluorometholone acetate ophthalmic suspension produced, on the average, a 47% reduction in the polymorphonuclear leukocytes invading the cornea during an experimentally induced inflammatory keratitis in New Zealand albino rabbits (1.5-2.0 kg) . Fluorometholone acetate (0.1%) formulated as a high-viscosity carbomer gel and applied at three-hour intervals reduced invading leukocytes in the cornea an average of 48%, an effect not significantly different from hourly administration of the suspension.
CAS Number
3801-06-7
Product Name Alternative
AI3-52814, Flarex, Fluorometholone acetate | U 17,323
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (238.95 mM)
Smiles
[H][C@@]12CC[C@] (OC (C) =O) (C (C) =O) [C@@]1 (C) C[C@] ([H]) (O) [C@@]1 (F) [C@@]2 ([H]) C[C@] ([H]) (C) C2=CC (=O) C=C[C@]12C
Molecular Formula
C24H31FO5
Molecular Weight
418.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate

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Alternative Products

CatalogName
FF23441-01Fluorometholone acetate
HY-B1471RFluorometholone acetate (Standard)
276366-01Δ-9 (11) -Fluorometholone acetate
FE22754-01(9b,11b) -Epoxy fluorometholone acetate
TRC-E589215-10MG(9Beta,11Beta)-Epoxy Fluorometholone Acetate
TRC-F593165-250MGdelta-9(11)-Fluorometholone Acetate
sc-497494(9β,11β) -Epoxy Fluorometholone Acetate

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