Products for Research Use Only

Icaritin

CAT: 0013-GTR19160003-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19160003-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Icaritin is an oral traditional Chinese medicine, derived from barrenwort, which targets the estrogen receptor α36. IC50 values for Icaritin are 8,13 and 18 μM for K562, CML-CP and CML-BC cells respectively. Icaritin inhibits the invasion and epithelial-to-mesenchymal transition of glioblastoma cells by targeting EMMPRIN via PTEN/AKt/HIF-1α signalling. Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway. Icaritin activates JNK-dependent mPTP necrosis pathway in colorectal cancer cells.
CAS Number
118525-40-9
Product Name Alternative
Icaritin
Purity
>98% (HPLC)
Solubility
DMSO : 14 mg/mL 38.00 mM
Smiles
CC (=CCc1c (cc (c2c1oc (c (c2=O) O) c1ccc (cc1) OC) O) O) C
Molecular Formula
C21H20O6
Molecular Weight
368.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3,5,7-Trihydroxy-2- (4-methoxyphenyl) -8- (3-methyl-2-buten-1-yl) -4H-1-benzopyran-4-one