Products for Research Use Only
RegisterLogin

PZM21

CAT: 0013-GTR19159909-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19159909-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PZM21 is a potent Gi activator with exceptional selectivity for μOR and minimal β-arrestin-2 recruitment. PZM21 is an experimental opioid analgesic drug that is being researched for the treatment of pain. It is a functionally selective μ-opioid receptor agonist which produces μ-opioid receptor mediated G protein signaling, with potency and efficacy similar to morphine, but with less β-arrestin 2 recruitment. In tests on mice, PZM21 was slightly less potent than morphine or TRV130 as an analgesic, but also had significantly reduced adverse effects, with less constipation than morphine, and very little respiratory depression, even at high doses.
CAS Number
1997387-43-5
Product Name Alternative
PZM21 | PZM-21 | PZM 21
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 72 mg/mL; 199.17 mM
Smiles
Oc1ccc (cc1) C[C@@H] (CNC (=O) N[C@@H] (C) Cc2ccsc2) N (C) C
Molecular Formula
C19H27N3O2S
Molecular Weight
361.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-[ (2S) -2- (Dimethylamino) -3- (4-hydroxyphenyl) propyl]-3-[ (2S) -1- (thiophen-3-yl) propan-2-yl]urea

Alternative Products

CatalogName
BA5635-1PZM21
A20586-25PZM21 25mg
A20586-2PZM21 2mg
A20586-100PZM21 100mg
A20586-50PZM21 50mg
A20586-5PZM21 5mg
A20586-1PZM21 1mg
A20586-10PZM21 10mg
HY-101386RPZM21 (Standard)

Popular Products