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Selamectin

CAT: 0013-GTR19159866-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19159866-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selamectin is a topical parasiticide and anthelminthic used on dogs and cats. It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats. (In Vitro) :The transport of radiolabelled Selamectin through Caco-2 monolayers shows that Selamectin is P-glycoprotein (P-gp) substrates with a secretory/absorptive ratio of 4.7. Selamectin inhibits the efflux of Rh-123 from peripheral blood lymphocytes (PBL) and the concentration of inhibition is similar to that of Verapamil. (In Vivo) :A single administration of 6 mg/kg topical Selamectin given every two months could effectively prevent B. malayi infection in cats. Application of topical Selamectin twice a year could block circulating microfilariae.
CAS Number
220119-17-5
Product Name Alternative
Selamectin | Revolution | Stronghold
Purity
>98% (HPLC)
Solubility
DMSO : 100 mg/mL 129.88 mM
Smiles
C/C/1=C\C[C@@H]2C[C@H] (OC (=O) [C@H]3[C@@]4 (/C (=C/C=C/[C@@H] ([C@@H]1O[C@H]1C[C@H] (OC) [C@@H] (O) [C@H] (C) O1) C) /CO[C@@H]4/C (=N\O) /C (=C3) C) O) C[C@]1 (CC[C@H] (C) [C@@H] (C3CCCCC3) O1) O2
Molecular Formula
C43H63NO11
Molecular Weight
769.96
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
A name could not be generated for this structure.

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C10842-5mgSelamectin

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