Products for Research Use Only

Cyclothiazide

CAT: 0013-GTR19159854-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19159854-01Size:1 g
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Description
Cyclothiazide (Anhydron, Acquirel, Doburil, Fluidil, Renazide, Tensodiural, Valmiran) is a benzothiadiazide (thiazide) diuretic and antihypertensive that was originally introduced in the United States in 1963 by Eli Lilly and was subsequently also marketed in Europe and Japan. This agent is capable of inhibiting rapid desensitization of the ionotropic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) -type glutamate receptors, thereby potentiating glutamate responses which may induce seizures activity. Cyclothiazide was also found to inhibit gamma-aminobutyric acid (GABA) -A receptors.
CAS Number
2259-96-3
Product Name Alternative
Cyclothiazide | Anhydron | Renazide | Valmiran
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (320.61 mM)
Smiles
NS (=O) (=O) c1cc2c (NC (NS2 (=O) =O) C2CC3CC2C=C3) cc1Cl
Molecular Formula
C14H16ClN3O4S2
Molecular Weight
389.9
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3- (bicyclo[2.2.1]hept-5-en-2-yl) -6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide

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