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PTP Inhibitor I

CAT: 0013-GTR19159817-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19159817-01Size:1 g
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Description
PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1 (ΔSH2) ) with a Ki value of 43 μM and PTP1B with a Ki value of 42 μM. SHP-1 and PTP1B both have known roles in regulating insulin signaling as well as myeloid and lymphoid cell differentiation, making inhibitors of these phosphatases of interest in diabetes, cancer, allergy, and inflammation research.
CAS Number
2491-38-5
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (1162.57 mM)
Smiles
Oc1ccc (cc1) C (=O) CBr
Molecular Formula
C8H7BrO2
Molecular Weight
215.04
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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