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Alpha-Hederin

CAT: 0013-GTR19159787-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159787-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alpha-Hederin is Derived from beta-amyrin; other hederigenin based saponins are available. It induces apoptosis in hepatocellular carcinoma cells. (In Vitro) :alpha-Hederin (α-Hederin) is cytotoxic and inhibits proliferation in both cel lines at rather low concentrations. alpha-Hederin (α-Hederin) reduces the mitotic activity in treated cells. (In Vivo) :alpha-Hederin (α-Hederin) has preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses.
CAS Number
27013-91-8
Product Name Alternative
Alpha-Hederin
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL 133.16 mM; H2O : < 0.1 mg/mL
Smiles
C[C@H]1[C@@H] ([C@H] ([C@H] ([C@@H] (O1) O[C@@H]1[C@H] ([C@H] (CO[C@H]1O[C@H]1CC[C@]2 ([C@H] ([C@]1 (C) CO) CC[C@@]1 ([C@@H]2CC=C2[C@]1 (CC[C@@]1 ([C@H]2CC (CC1) (C) C) C (=O) O) C) C) C) O) O) O) O) O
Molecular Formula
C41H66O12
Molecular Weight
750.97
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(4alpha) -3beta- ((2-O- (6-Deoxy-alpha-L-mannopyranosyl) -alpha-L-arabinopyranosyl) oxy) -23-hydroxyolean-12-en-28-oic acid

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