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Tirapazamine

CAT: 0013-GTR19159783-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159783-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trapazamine, also known as SR-4233, DNA-damaging drug potentially for the treatment of cervical carcinoma, head and neck cancer. Tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors. Cells in these regions are resistant to killing by radiotherapy and most anticancer drugs. Thus the combination of tirapazamine with conventional anticancer treatments is particularly effective. (In Vitro) :Tirapazamine (SR259075) is the optimal drug for combination therapy using Pba. (In Vivo) :Tirapazamine (SR259075) (1mg; intravenously injected; twice at a 24-h interval) shows a synergetic effect to kill tumor cells because TPZ was activated under the hypoxic conditions that originated from the PDT with Pba and laser irradiation. .
CAS Number
27314-97-2
Product Name Alternative
Tirapazamine | Tirazone | SR 4233 | SR-4233 | WIN 59075
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 39 mg/m; 218.92 mM
Smiles
Nc1nn (=O) c2ccccc2n1=O
Molecular Formula
C7H6N4O2
Molecular Weight
178.15
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-aminobenzo[e][1,2,4]triazine 1,4-dioxide

Alternative Products

CatalogName
202940Tirapazamine
A12754-1000Tirapazamine 1000mg
A12754-250Tirapazamine 250mg
A12754-25Tirapazamine 25mg
A12754-10Tirapazamine 10mg
A12754-500Tirapazamine 500mg
A12754-100Tirapazamine 100mg
A12754-50Tirapazamine 50mg
A12754-10mM-DTirapazamine 10mM * 1mL in DMSO
MBS6065891-013-Amino-1,2,4-benzotriazine-1,4-dioxide (SR-4233, Tirapazamine)

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