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Biapenem

CAT: 0013-GTR19159762-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159762-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Biapenem is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. Biapenem has similar antibacterial activity to that of imipenem, but is more stable against human renal dehydropeptidase-I and with less neurotoxicity. (In Vitro) :Biapenem (CLI 86815) is a carbapenem antibiotic of in vitro antibacterial activity encompassing many Gramnegative and Gram-positive aerobic and anaerobic bacteria, including species producing β-lactamases. Biapenem (CLI 86815) is more stable than imipenem, mero-penem and panipenem to hydrolysis by human renal dihydropeptidase-I (DHP-I), and therefore does not require the coadministration of a DHP-I inhibitor. In randomised, nonblind or double-blind clinical trials, biapenem showed good clinical and bacteriological efficacy (similar to that of imipenem/ cilastatin) in the treatment of adult patients with intra-abdominal infections, lower respiratory infections or complicated urinary tract infections.
CAS Number
120410-24-4
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
H2O : 20 mg/mL 57.08 mM
Smiles
[n+]12n (cnc1) CC (C2) SC1=C (N2[C@H] ([C@H]1C) [C@H] (C2=O) [C@@H] (C) O) C (=O) [O-]
Molecular Formula
C15H18N4O4S
Molecular Weight
350.39
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(4R,5S,6S) -3- ((6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-yl) thio) -6- (1-hydroxyethyl) -4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

Alternative Products

CatalogName
A1373-5.1Biapenem

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