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Naratriptan hydrochloride

CAT: 0013-GTR19159636-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19159636-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.
CAS Number
143388-64-1
Product Name Alternative
Naratriptan HCl | Amerge | Naramig | GR-85548A
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 35 mg/mL; 94.10 mM
Smiles
CNS (=O) (=O) CCc1cc2c (cc1) [nH]cc2C1CCN (CC1) C.Cl
Molecular Formula
C17H25N3O2S·HCl
Molecular Weight
371.93
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N-Methyl-2-[3- (1-methylpiperidin-4-yl) -1H-indol-5-yl]ethanesulfonamide hydrochloride

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