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BAY1217389

CAT: 0013-GTR19159577-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159577-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY1217389 is an orally bioavailable, selective inhibitor of the serine/threonine kinase monopolar spindle 1 (Mps1, TTK), with potential antineoplastic activity. Upon administration, the Mps1 inhibitor BAY 1217389 selectively binds to and inhibits the activity of Mps1. This inactivates the spindle assembly checkpoint (SAC), accelerates mitosis, causes chromosomal misalignment and missegregation, and mitotic checkpoint complex destabilization. This induces cell death in Mps1-overexpressing cancer cells.
CAS Number
1554458-53-5
Product Name Alternative
BAY1217389 | BAY-1217389 | BAY 1217389
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 28 mg/mL; 49.87 mM
Smiles
Cc1c (ccc (c1) c1cnc2n1nc (cc2NCCC (F) (F) F) Oc1c (c (c (cc1) OC) F) F) C (=O) NC1CC1
Molecular Formula
C27H24F5N5O3
Molecular Weight
561.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N-cyclopropyl-4- (6- (2,3-difluoro-4-methoxyphenoxy) -8- ((3,3,3-trifluoropropyl) amino) imidazo[1,2-b]pyridazin-3-yl) -2-methylbenzamide

Alternative Products

CatalogName
206545BAY1217389
A21595-5BAY1217389 5mg
A21595-1BAY1217389 1mg
A21595-25BAY1217389 25mg
A21595-2BAY1217389 2mg
A21595-50BAY1217389 50mg
A21595-10BAY1217389 10mg
A21595-10mM-DBAY1217389 10mM * 1mL in DMSO

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