Products for Research Use Only
RegisterLogin

Y16

CAT: 0013-GTR19159488-04Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19159488-04Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Y16, also known as RhoA-IN-Y16, is a RhoA inhibitor, Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM) . Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells.
CAS Number
429653-73-6
Product Name Alternative
RhoA-IN-Y16 | Y16
Purity
>98% (HPLC)
Solubility
DMSO : 25 mg/mL 65.03 mM; H2O : < 0.1 mg/mL
Smiles
Cc1cc (ccc1) COc1cccc (c1) C=C1C (=O) NN (C1=O) c1ccccc1
Molecular Formula
C24H20N2O3
Molecular Weight
384.43
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -4- (3- ((3-methylbenzyl) oxy) benzylidene) -1-phenylpyrazolidine-3,5-dione

Chemical Information

(4E)-4-[[3-[(3-methylphenyl)methoxy]phenyl]methylidene]-1-phenylpyrazolidine-3,5-dione
CAS Number429653-73-6
PubChem CID989521
IUPAC Name(4E)-4-[[3-[(3-methylphenyl)methoxy]phenyl]methylidene]-1-phenylpyrazolidine-3,5-dione
Molecular FormulaC24H20N2O3
Molecular Weight384.4
XLogP4.7
Topological Polar Surface Area58.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Heavy Atom Count29
Formal Charge0
Complexity626
SMILES
CC1=CC(=CC=C1)COC2=CC=CC(=C2)/C=C/3\C(=O)NN(C3=O)C4=CC=CC=C4
InChI
InChI=1S/C24H20N2O3/c1-17-7-5-9-19(13-17)16-29-21-12-6-8-18(14-21)15-22-23(27)25-26(24(22)28)20-10-3-2-4-11-20/h2-15H,16H2,1H3,(H,25,27)/b22-15+
InChIKey
ITMLWGWTDWJSRZ-PXLXIMEGSA-N
Chemical Structure
2D Structure
2D structure of (4E)-4-[[3-[(3-methylphenyl)methoxy]phenyl]methylidene]-1-phenylpyrazolidine-3,5-dione
CAS: 429653-73-6
CID: 989521
Formula: C24H20N2O3
MW: 384.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight384.4
XLogP34.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass384.14739250
Monoisotopic Mass384.14739250
Topological Polar Surface Area58.6 Ų
Heavy Atom Count29
Formal Charge0
Complexity626
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR17992661Y16O Antibody
GTR17992660Y16K Antibody
GTR17998600Y16M Antibody
GTR17992824Y16F Antibody
GTR17992659Y16H Antibody
GTR17992672Y16B Antibody
GTR17992671Y16A Antibody
GTR17992662Y16Q Antibody
GTR17992656Y16D Antibody
GTR17992835Y16J Antibody

Alternative Products

CatalogName
303-150Riboclear (RNA Cleanup)
TBS10485-100Tribio InVivoMAb Anti-Mouse TIGIT & PD-L1 Bispecific Antibody
TBS10191-1mgTetrahydrocannabinol (THC) Monoclonal Antibody
TBI3024-25MGAc-Leu-Leu-Nle-CHO (ALLN), Calpain inhibitor
122-101ExgeneTM Forensic SV mini
TBS10483-100Tribio InVivoMAb Anti-Mouse PD-L1 & CD28 Bispecific Antibody
TBS10183-1mgMonoclonal Anti-Thyroid Stimulating Hormone (TSH) Antibody
TBS10340-0.5MGInVivo Mouse IgG1 Isotype Control Antibody
121-220Exfection Plasmid EF (Exdotoxin Free, Midi)
TBS10482-100Tribio InVivoMAb Anti-Mouse PD-L1 & OX40 Bispecific Antibody

Popular Products