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NS1643

CAT: 0013-GTR19159473-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19159473-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NS-1643 is a Human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM) . NS1643 increased both steady-state and tail current at all voltages tested. The EC (50) value for HERG channel activation was 10.5 microM. HERG channel activation by small molecules such as NS1643 increases the repolarization reserve and presents an interesting new antiarrhythmic approach.
CAS Number
448895-37-2
Product Name Alternative
NS-1643 | NS 1643 | NS1643
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL; 262.99 mM
Smiles
C1c (ccc (c1NC (=O) Nc1c (O) ccc (c1) C (F) (F) F) O) C (F) (F) F
Molecular Formula
C15H10F6N2O3
Molecular Weight
380.24
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,3-bis (2-hydroxy-5- (trifluoromethyl) phenyl) urea

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Alternative Products

CatalogName
M18560-01NS1643
217419Herg Activator (NS1643, 1,3-bis- (2-hydroxy-5-trifluoromethyl-phenyl) -urea, Human ether-a-go-go related gene (hERG) K+ channel activator, KV11.1 Channel Activator)

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