Products for Research Use Only

Corylifol A

CAT: 0013-GTR19159409-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159409-01Size:200 mg
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Description
Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. Corylifol A and Biochanin A can be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. Corylifol A and bavachin are strong inhibitors of UDP-glucuronosyltransferase 1A1 (UGT1A1) with the inhibition kinetic parameters (Ki) values lower than 1 uM.Corylifol A and bakuchiol are naturally occurring potent inhibitors of hCE2, with low Ki values ranging from 0.62uM to 3.89 uM. Corylifol A shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uμ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells, suggests that corylifol A has antiinflammatory activity.
CAS Number
775351-88-7
Product Name Alternative
Corylifol-A | Corylinin
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 15.4 mg/mL; 39.44 mM
Smiles
CC (=CCCC (=CCC1=C (C=CC (=C1) C2=COC3=C (C2=O) C=CC (=C3) O) O) C) C
Molecular Formula
C25H26O4
Molecular Weight
390.47
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.