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Glaucocalyxin A

CAT: 0013-GTR19159397-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159397-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expression of X-linked inhibitor of apoptosis protein. Glaucocalyxin A inhibits Akt phosphorylation, suppresses proliferation, and promotes apoptosis in a dose-dependent manner, but not in normal glial cells. Glaucocalyxin A inhibits collagen-stimulated tyrosine phosphorylation of Syk, LAT, and phospholipase Cγ2, the signaling events in collagen receptor GPVI pathway. Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand.
CAS Number
79498-31-0
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (150.41 mM)
Smiles
CC1 (C2CC (C34C (C2 (CCC1=O) C) CCC (C3O) C (=C) C4=O) O) C
Molecular Formula
C20H28O4
Molecular Weight
332.44
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
TRL0079Glaucocalyxin A
TBW01265Glaucocalyxin D
HY-N2113-01Glaucocalyxin B
TN6258Glaucocalyxin A diacetate

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