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Sulfaphenazole

CAT: 0013-GTR19159092-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159092-01Size:200 mg
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Description
Sulfaphenazole is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19) . At 10 μM, sulfaphenazole has been shown to inhibit endothelium-derived hyperpolarizing factor synthase, a CYP450 isozyme in the porcine coronary artery homologous to CYP2C8/9 that generates reactive oxygen species in coronary endothelial cells and modulates vascular tone and homeostasis.
CAS Number
526-08-9
Product Name Alternative
BRN-0308518 | Sulfaphenazole | Firmazolo | Inamil
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL; 318.11 mM
Smiles
Nc1ccc (cc1) S (=O) (=O) Nc1ccnn1-c1ccccc1
Molecular Formula
C15H14N4O2S
Molecular Weight
314.36
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-amino-N- (1-phenyl-1H-pyrazol-5-yl) benzenesulfonamide

Alternative Products

CatalogName
C4131-50Sulfaphenazole

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